BRD2 monoclonal antibody, clone 1H6B12
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: BRD2-hIgGFc transfected HEK293 cell lysates with BRD2 monoclonal antibody, clone 1H6B12 (Cat # MAB17886).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with BRD2 monoclonal antibody, clone 1H6B12 (Cat # MAB17886).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human BRD2.
Immunogen
Recombinant protein corresponding to amino acids 227-364 of human BRD2.
Host
Mouse
Theoretical MW (kDa)
88
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: BRD2-hIgGFc transfected HEK293 cell lysates with BRD2 monoclonal antibody, clone 1H6B12 (Cat # MAB17886).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with BRD2 monoclonal antibody, clone 1H6B12 (Cat # MAB17886). -
Gene Info — BRD2
Entrez GeneID
6046Protein Accession#
P25440Gene Name
BRD2
Gene Alias
D6S113E, DKFZp686N0336, FLJ31942, FSH, FSRG1, KIAA9001, NAT, RING3, RNF3
Gene Description
bromodomain containing 2
Omim ID
601540Gene Ontology
HyperlinkGene Summary
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000029350|bromodomain-containing 2|female sterile homeotic-related gene 1
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Interactome
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Disease
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