CSF1R monoclonal antibody, clone 6B9B9
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CSF1R-hIgGFc transfected HEK293 cell lysates with CSF1R monoclonal antibody, clone 6B9B9 (Cat # MAB17880).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with CSF1R monoclonal antibody, clone 6B9B9 (Cat # MAB17880).
Immunofluorescence
Immunofluorescent staining of HepG2 cells with CSF1R monoclonal antibody, clone 6B9B9 (Cat # MAB17880) (Green). Blue: DRAQ5 fluorescent DNA dye.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CSF1R monoclonal antibody, clone 6B9B9 (Cat # MAB17880).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CSF1R.
Immunogen
Recombinant protein corresponding to amino acids 344-497 of human CSF1R.
Host
Mouse
Theoretical MW (kDa)
108
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Immunofluorescence (1:200-1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CSF1R-hIgGFc transfected HEK293 cell lysates with CSF1R monoclonal antibody, clone 6B9B9 (Cat # MAB17880).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with CSF1R monoclonal antibody, clone 6B9B9 (Cat # MAB17880).Immunofluorescence
Immunofluorescent staining of HepG2 cells with CSF1R monoclonal antibody, clone 6B9B9 (Cat # MAB17880) (Green). Blue: DRAQ5 fluorescent DNA dye.Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CSF1R monoclonal antibody, clone 6B9B9 (Cat # MAB17880). -
Gene Info — CSF1R
Entrez GeneID
1436Protein Accession#
P07333Gene Name
CSF1R
Gene Alias
C-FMS, CD115, CSFR, FIM2, FMS
Gene Description
colony stimulating factor 1 receptor
Omim ID
164770Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq
Other Designations
CD115 antigen|FMS proto-oncogene|McDonough feline sarcoma viral (v-fms) oncogene homolog|macrophage colony stimulating factor I receptor|soluble CSF1R variant 1
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Interactome
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Pathway
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Disease
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