PDX1 monoclonal antibody, clone 5A5
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More Files
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Enzyme-linked Immunoabsorbent Assay
ELISA analysis with PDX1 monoclonal antibody, clone 5A5 (Cat # MAB17872).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human PDX1.
Immunogen
Recombinant protein corresponding to amino acids 39-283 of human PDX1.
Host
Mouse
Theoretical MW (kDa)
30.8
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with PDX1 monoclonal antibody, clone 5A5 (Cat # MAB17872).Flow Cytometry
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Gene Info — PDX1
Entrez GeneID
3651Protein Accession#
P52945Gene Name
PDX1
Gene Alias
GSF, IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1
Gene Description
pancreatic and duodenal homeobox 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq
Other Designations
OTTHUMP00000018174|glucose-sensitive factor|insulin promoter factor 1, homeodomain transcription factor|insulin upstream factor 1|pancreatic-duodenal homeobox factor 1|somatostatin transcription factor 1
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Interactome
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Pathway
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Disease
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