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Last updated: 2020/1/26

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TYK2 monoclonal antibody, clone 8G8B3 

  • Catalog # : MAB17865
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant human TYK2.
  • Immunogen:
  • Recombinant protein corresponding to human TYK2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:100-1:500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascitic fluid (0.03% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of Lane 1: TYK2 recombinant protein and Lane 2: Jurkat cell lysate with TYK2 monoclonal antibody, clone 8G8B3 (Cat # MAB17865).
  • Enzyme-linked Immunoabsorbent Assay
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Gene Information
  • Entrez GeneID:
  • 7297
  • Gene Name:
  • TYK2
  • Gene Alias:
  • JTK1
  • Gene Description:
  • tyrosine kinase 2
  • Gene Summary:
  • This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq
  • Other Designations:
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