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Last updated: 2017/5/21
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THRB monoclonal antibody, clone 2386

  • Catalog # : MAB1784
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of THRB.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus human THRB.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 55
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot of hippocampal lysate showing specific immunolabeling of the ~58k THRB protein. Using THRB monoclonal antibody, clone 2386 (Cat # MAB1784).
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7068
  • Gene Name:
  • THRB
  • Gene Alias:
  • ERBA-BETA,ERBA2,GRTH,MGC126109,MGC126110,NR1A2,PRTH,THR1,THRB1,THRB2
  • Gene Description:
  • thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
  • Gene Summary:
  • The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000161044,avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2,oncogene ERBA2,thyroid hormone receptor beta 1,thyroid hormone receptor beta isoform,thyroid hormone receptor, beta
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