FCER1A monoclonal antibody, clone 1F2A9
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot (Tissue lysate) analysis of mouse kidney tissue lysate.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of FCER1A monoclonal antibody.
Flow Cytometry
Flow cytometric analysis of HEK293 cells using FCER1A mouse monoclonal antibody (green) and negative control (red).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human FCER1A.
Immunogen
Recombinant protein corresponding to amino acids 42-103 of human FCER1A from E. coli.
Host
Mouse
Theoretical MW (kDa)
29.6
Reactivity
Human, Mouse
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot (Tissue lysate) analysis of mouse kidney tissue lysate.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of FCER1A monoclonal antibody.Flow Cytometry
Flow cytometric analysis of HEK293 cells using FCER1A mouse monoclonal antibody (green) and negative control (red). -
Gene Info — FCER1A
Entrez GeneID
2205Gene Name
FCER1A
Gene Alias
FCE1A, FcERI
Gene Description
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Omim ID
147140Gene Ontology
HyperlinkGene Summary
The IgE receptor plays a central role in allergic disease, coupling allergen and mast cell to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The allergic response occurs when 2 or more high-affinity IgE receptors are crosslinked via IgE molecules that in turn are bound to an allergen (antigen) molecule. A perturbation occurs that brings about the release of histamine and proteases from the granules in the cytoplasm of the mast cell and leads to the synthesis of prostaglandins and leukotrienes--potent effectors of the hypersensitivity response. The IgE receptor consists of 3 subunits: alpha, beta (MIM 147138), and gamma (MIM 147139); only the alpha subunit is glycosylated.[supplied by OMIM
Other Designations
Fc IgE receptor, alpha polypeptide|Fc epsilon RI alpha-chain|Fc-epsilon RI-alpha|high affinity immunoglobulin epsilon receptor alpha-subunit|immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide
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Interactome
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Pathway
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Disease
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