TERF2 monoclonal antibody, clone 3H6B4
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Specifications
Product Description
Mouse monoclonal antibody raised against recombinant human TERF2.
Immunogen
Recombinant protein corresponding to amino acids 324-500 of human TERF2 from E. coli.
Host
Mouse
Theoretical MW (kDa)
55.6
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry
Immunocytochemistry
Immunohistochemistry (1:200-1:1000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) TERF2-hIgGFc transfected HEK293 cell lysate with TERF2 monoclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded ovarian cancer tissue with TERF2 monoclonal antibody.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of TERF2 monoclonal antibody, clone 3H6B4. -
Gene Info — TERF2
Entrez GeneID
7014Gene Name
TERF2
Gene Alias
TRBF2, TRF2
Gene Description
telomeric repeat binding factor 2
Omim ID
602027Gene Ontology
HyperlinkGene Summary
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq
Other Designations
telomeric repeat binding protein 2
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Interactomes
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Diseases
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