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Last updated: 2019/12/8

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STAT6 monoclonal antibody, clone 7D3 

  • Catalog # : MAB17700
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant human STAT6.
  • Immunogen:
  • Recombinant protein corresponding to human STAT6 from E. coli.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 94
  • Reactivity:
  • Human, Monkey, Mouse, Rat
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry
    Immunocytochemistry (1:200-1:1000)
    Immunohistochemistry
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of (1) HEK293 cell, (2) NIH/3T3 cell, (3) MCF-7 cell, (4) Raw246.7 cell, (5) PC-12 cell with STAT6 monoclonal antibody.
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemical staining of HeLa cells with STAT6 monoclonal antibody (green). DRAQ5 fluorescent DNA dye (blue). Actin filaments labeled with Alexa Fluor-555 phalloidin (red).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6778
  • Gene Name:
  • STAT6
  • Gene Alias:
  • D12S1644,IL-4-STAT,STAT6B,STAT6C
  • Gene Description:
  • signal transducer and activator of transcription 6, interleukin-4 induced
  • Gene Summary:
  • The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq
  • Other Designations:
  • STAT, interleukin4-induced,signal transducer and activator of transcription 6,transcription factor IL-4 STAT
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