PARL monoclonal antibody, clone 8C4B2
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis of truncated (1) Trx-PARL recombinant protein and (2) MBP-PARL recombinant protein with PARL monoclonal antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human PARL.
Immunogen
Recombinant protein corresponding to amino acids 112-167 of human PARL from E. coli.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Flow Cytometry
Immunocytochemistry
Immunohistochemistry
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis of truncated (1) Trx-PARL recombinant protein and (2) MBP-PARL recombinant protein with PARL monoclonal antibody. -
Gene Info — PARL
Entrez GeneID
55486Gene Name
PARL
Gene Alias
PRO2207, PSARL, PSARL1, PSENIP2, RHBDS1
Gene Description
presenilin associated, rhomboid-like
Omim ID
607858Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
mitochondrial intramembrane-cleaving protease PARL|rhomboid 7 homolog 1
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Interactome
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Disease
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