EPHA1 monoclonal antibody, clone 5D2
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human EPHA1.
Immunogen
Recombinant protein corresponding to human EPHA1 from E. coli.
Host
Mouse
Theoretical MW (kDa)
108
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry
Immunocytochemistry
Immunohistochemistry (1:200-1:1000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.03% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of (1) A549 cell, (2) HeLa cell with EPHA1 monoclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human ovary carcinoma (left) and breast carcinoma (right) with EPHA1 monoclonal antibody. -
Gene Info — EPHA1
Entrez GeneID
2041Gene Name
EPHA1
Gene Alias
EPH, EPHT, EPHT1, MGC163163
Gene Description
EPH receptor A1
Omim ID
179610Gene Ontology
HyperlinkGene Summary
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq
Other Designations
eph tyrosine kinase 1|ephrin receptor EphA1|ephrin type-A receptor 1|erythropoietin-producing hepatoma amplified sequence|oncogene EPH|soluble EPHA1 variant 1|soluble EPHA1 variant 2|tyrosine-protein kinase receptor EPH
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Interactome
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Pathway
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Disease
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