CCR1 monoclonal antibody, clone 8E10F9
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell with CCR1 monoclonal antibody.
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) CCR1-hIgGFc transfected HEK293 cell lysate.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of CCR1 monoclonal antibody, clone 8E10F9.
Flow Cytometry
Flow cytometric analysis of Ramos cells with CCR1 monoclonal antibody (green) and negative control (red).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human CCR1.
Immunogen
Recombinant protein corresponding to amino acid of human CCR1 from E. coli.
Host
Mouse
Theoretical MW (kDa)
41.2
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunocytochemistry
Flow Cytometry (1:200-1:400)
Immunohistochemistry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell with CCR1 monoclonal antibody.Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) CCR1-hIgGFc transfected HEK293 cell lysate.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of CCR1 monoclonal antibody, clone 8E10F9.Flow Cytometry
Flow cytometric analysis of Ramos cells with CCR1 monoclonal antibody (green) and negative control (red). -
Gene Info — CCR1
Entrez GeneID
1230Gene Name
CCR1
Gene Alias
CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
Gene Description
chemokine (C-C motif) receptor 1
Omim ID
601159Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq
Other Designations
RANTES receptor
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Interactome
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Pathway
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Disease
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