IL2RB monoclonal antibody, clone 1G11H3
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) IL2RB-hIgGFc transfected HEK293 cell lysate.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of IL2RB monoclonal antibody, clone 1G11H3.
Flow Cytometry
Flow cytometric analysis of Ramos cells with IL2RB monoclonal antibody (green) and negative control (red).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human IL2RB.
Immunogen
Recombinant protein corresponding to amino acid 27-240 of human IL2RB from E. coli.
Host
Mouse
Theoretical MW (kDa)
61
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunocytochemistry
Flow Cytometry (1:200-1:400)
Immunohistochemistry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) IL2RB-hIgGFc transfected HEK293 cell lysate.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of IL2RB monoclonal antibody, clone 1G11H3.Flow Cytometry
Flow cytometric analysis of Ramos cells with IL2RB monoclonal antibody (green) and negative control (red). -
Gene Info — IL2RB
Entrez GeneID
3560Gene Name
IL2RB
Gene Alias
CD122, P70-75
Gene Description
interleukin 2 receptor, beta
Omim ID
146710Gene Ontology
HyperlinkGene Summary
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq
Other Designations
CD122 antigen|OTTHUMP00000028799|high affinity IL-2 receptor beta subunit|interleukin 2 receptor beta
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Interactome
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Pathway
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Disease
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