CD207 monoclonal antibody, clone 1C5A1
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) CD207-hIgGFc transfected HEK293 cell lysate.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of CD207 monoclonal antibody, clone 1C5A1.
Flow Cytometry
Flow cytometric analysis of K562 cells with CD207 monoclonal antibody (green) and negative control (red).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human CD207.
Immunogen
Recombinant protein corresponding to amino acid 155-328 of human CD207 from E. coli.
Host
Mouse
Theoretical MW (kDa)
36.7
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunocytochemistry
Flow Cytometry (1:200-1:400)
Immunohistochemistry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) CD207-hIgGFc transfected HEK293 cell lysate.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of CD207 monoclonal antibody, clone 1C5A1.Flow Cytometry
Flow cytometric analysis of K562 cells with CD207 monoclonal antibody (green) and negative control (red). -
Gene Info — CD207
Entrez GeneID
50489Gene Name
CD207
Gene Alias
CLEC4K
Gene Description
CD207 molecule, langerin
Omim ID
604862Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. [provided by RefSeq
Other Designations
C-type lectin domain family 4, member K|CD207 antigen, langerin|Langerhans cell specific c-type lectin
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Interactome
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