GRIK2 monoclonal antibody, clone 8A1F11
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human GRIK2.
Immunogen
Recombinant protein corresponding to amino acid 45-226 of human GRIK2 from E. coli.
Host
Mouse
Theoretical MW (kDa)
102.5
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunocytochemistry
Flow Cytometry
Immunohistochemistry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) GRIK2-hIgGFc transfected HEK293 cell lysate.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of GRIK2 monoclonal antibody, clone 8A1F11. -
Gene Info — GRIK2
Entrez GeneID
2898Gene Name
GRIK2
Gene Alias
EAA4, GLR6, GLUK6, GLUR6, MGC74427, MRT6
Gene Description
glutamate receptor, ionotropic, kainate 2
Gene Ontology
HyperlinkGene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation. [provided by RefSeq
Other Designations
OTTHUMP00000017949|bA487F5.1|excitatory amino acid receptor 4|glutamate receptor 6
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