ADRB2 monoclonal antibody, clone 4A6C9
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) ADRB2-hIgGFc transfected HEK293 cell lysate.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of ADRB2 monoclonal antibody, clone 4A6C9.
Flow Cytometry
Flow cytometric analysis of Hela cells with ADRB2 monoclonal antibody (green) and negative control (red).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human ADRB2.
Immunogen
Recombinant protein corresponding to amino acid 302-413 of human ADRB2 from E. coli.
Host
Mouse
Theoretical MW (kDa)
46.5
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry
Immunocytochemistry
Flow Cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) ADRB2-hIgGFc transfected HEK293 cell lysate.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of ADRB2 monoclonal antibody, clone 4A6C9.Flow Cytometry
Flow cytometric analysis of Hela cells with ADRB2 monoclonal antibody (green) and negative control (red). -
Gene Info — ADRB2
Entrez GeneID
154Gene Name
ADRB2
Gene Alias
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Gene Description
adrenergic, beta-2-, receptor, surface
Gene Ontology
HyperlinkGene Summary
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq
Other Designations
beta-2 adrenergic receptor|beta-2 adrenoceptor|catecholamine receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast cancer: a randomized controlled trial.
Grace M Niemiro, Adriana M Coletta, Nadia H. Agha, Preteesh Leo Mylabathula, Forrest L. Baker, Abenaa M Brewster, Therese B Bevers, Enrique Fuentes-Mattei, Karen Basen-Engquist, Emmanuel Katsanis, Susan C Gilchrist, Richard J. Simpson.
Immunity & Ageing 2022 Mar; 19(1):17.
Application：Flow cyt, Human, Human blood.
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Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast cancer: a randomized controlled trial.
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