O3FAR1 monoclonal antibody, clone 2B6
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of O3FAR1.
Immunogen
A synthetic peptide corresponding to human O3FAR1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2a, kappa
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Immunoprecipitation (5 ug/mL)
Flow Cyt (1-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2.0% Block Ace)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunofluorescence
Immunofluorescence analysis of HEK 293T cells overexpressing human O3FAR1, using O3FAR1 monoclonal antibody, clone 2B6 (Cat # MAB1725) .Flow Cytometry
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Gene Info — O3FAR1
Entrez GeneID
338557Gene Name
O3FAR1
Gene Alias
BMIQ10, GPR120, GPR129, GT01, PGR4
Gene Description
omega-3 fatty acid receptor 1
Omim ID
609044Gene Ontology
HyperlinkGene Summary
GPR120 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et al., 2003 [PubMed 14623098]).[supplied by OMIM
Other Designations
G-protein coupled receptor 120; G-protein coupled receptor 129; G-protein coupled receptor GT01; G-protein coupled receptor PGR4
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Disease
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Publication Reference
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GPR expression in the rat taste bud relating to fatty acid sensing.
Matsumura S, Mizushige T, Yoneda T, Iwanaga T, Tsuzuki S, Inoue K, Fushiki T.
Biomedical Research (Tokyo, Japan) 2007 Feb; 28(1):49.
Application:IHC-P, WB-Ti, Rat, Rat circumvallate papillae, colon, tongue.
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The regulation of adipogenesis through GPR120.
Gotoh C, Hong YH, Iga T, Hishikawa D, Suzuki Y, Song SH, Choi KC, Adachi T, Hirasawa A, Tsujimoto G, Sasaki S, Roh SG.
Biochemical and Biophysical Research Communications 2007 Mar; 354(2):591.
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Free fatty acids inhibit serum deprivation-induced apoptosis through GPR120 in a murine enteroendocrine cell line STC-1.
Katsuma S, Hatae N, Yano T, Ruike Y, Kimura M, Hirasawa A, Tsujimoto G.
The Journal of Biological Chemistry 2005 May; 280(20):19507.
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Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.
Hirasawa A, Tsumaya K, Awaji T, Katsuma S, Adachi T, Yamada M, Sugimoto Y, Miyazaki S, Tsujimoto G.
Nature Medicine 2005 Jan; 11(1):90.
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GPR expression in the rat taste bud relating to fatty acid sensing.
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