TFRC monoclonal antibody, clone YUK9
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Specification
Product Description
Mouse monoclonal antibody raised against native TFRC.
Immunogen
Native purified from human cancer cel line.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1, kappa
Quality Control Testing
Antibody Reactive Against TFRC.
Recommend Usage
Flow Cyt (1-5 ug/mL)
Immunoprecipitation (5-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% proclin, 2.0% Block Ace)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunoprecipitation
Flow Cytometry
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Gene Info — TFRC
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Interactome
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Pathway
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Disease
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Publication Reference
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A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid.
Kasibhatla S, Jessen KA, Maliartchouk S, Wang JY, English NM, Drewe J, Qiu L, Archer SP, Ponce AE, Sirisoma N, Jiang S, Zhang HZ, Gehlsen KR, Cai SX, Green DR, Tseng B.
PNAS 2005 Aug; 102(34):12095.
Application:IF, WB, WB-Tr, Human, Jurkat, T47D, 293T cells.
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The transferrin receptor: a potential molecular imaging marker for human cancer.
Hogemann-Savellano D, Bos E, Blondet C, Sato F, Abe T, Josephson L, Weissleder R, Gaudet J, Sgroi D, Peters PJ, Basilion JP.
Neoplasia 2003 Nov; 5(6):495.
Application:WB, Human, BT20, BT549, HBL100, MCF-7. MCF10A cells.
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A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients.
Moura IC, Lepelletier Y, Arnulf B, England P, Baude C, Beaumont C, Bazarbachi A, Benhamou M, Monteiro RC, Hermine O.
Blood 2003 Oct; 103(5):1838.
Application:Flow Cyt, Func, Human, Tumor cells from a patient with chronic Adult T-cell leukemia/lymphoma (ATL), PBMCs.
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Transferrin receptor 1 is differentially required in lymphocyte development.
Ned RM, Swat W, Andrews NC.
Blood 2003 Nov; 102(10):3711.
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Transferrin receptor in T cell activation and transplantation.
Bayer AL, Baliga P, Woodward JE.
Journal of Leukocyte Biology 1998 Jul; 64(1):19.
Application:Treated, Recombinant protein.
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A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid.
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