SIRT7 monoclonal antibody, clone 1E2G10
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human SIRT7.
Immunogen
Recombinant protein corresponding to amino acid 1-105 of human SIRT7 from E. coli.
Host
Mouse
Theoretical MW (kDa)
44.9kDa
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Immunocytochemistry
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of (1) HEK293 cells, (2) SIRT7-hIgGFc transfected HEK293 cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded liver cancer tissues with SIRT7 monoclonal antibody.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of SIRT7 monoclonal antibody, clone 1E2G10. -
Gene Info — SIRT7
Entrez GeneID
51547Gene Name
SIRT7
Gene Alias
MGC126840, MGC126842, SIR2L7
Gene Description
sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
Omim ID
606212Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq
Other Designations
silent mating type information regulation 2, S.cerevisiae, homolog 7|sir2-related protein type 7|sirtuin 7|sirtuin type 7
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