SERPINF1 monoclonal antibody, clone 14K
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More Files
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Western Blot (Cell lysate)
Western blot analysis of extract from retinal pigment epithelium, using SERPINF1 monoclonal antibody, clone 14K (Cat # MAB1712) .
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of SERPINF1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to human SERPINF1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western Blot (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% BSA, 0.1% proclin)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blot analysis of extract from retinal pigment epithelium, using SERPINF1 monoclonal antibody, clone 14K (Cat # MAB1712) . -
Gene Info — SERPINF1
Entrez GeneID
5176Gene Name
SERPINF1
Gene Alias
EPC-1, PEDF, PIG35
Gene Description
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Omim ID
172860Gene Ontology
HyperlinkGene Summary
The PEDF gene is a member of the serpin gene family. Serpins are a group of serine protease inhibitors, some of which have also been reported to exhibit neurotrophic activity.[supplied by OMIM
Other Designations
pigment epithelium-derived factor|proliferation-inducing protein 35|serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
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Interactome
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Disease
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Publication Reference
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Loss of the antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye disease.
Spranger J, Osterhoff M, Reimann M, Mohlig M, Ristow M, Francis MK, Cristofalo V, Hammes HP, Smith G, Boulton M, Pfeiffer AF.
Diabetes 2001 Dec; 50(12):2641.
Application：ELISA, IHC, WB-Re, WB-Tr, Human, Intraocular samples, Recombinant protein, Retinal samples, Vitreal samples.
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Pigment epithelium-derived factor: a potent inhibitor of angiogenesis.
Dawson DW, Volpert OV, Gillis P, Crawford SE, Xu H, Benedict W, Bouck NP.
Science 1999 Jul; 285(5425):245.
Application：Func, IHC, WB-Ce, WB-Tr, Human, Mouse, Human dermal microvascular endothelial cells, Mouse retinas, WERI-Rb-1 cells.
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Recombinant human pigment epithelium-derived factor (PEDF): characterization of PEDF overexpressed and secreted by eukaryotic cells.
Stratikos E, Alberdi E, Gettins PG, Becerra SP.
Protein Science 1996 Dec; 5(12):2575.
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Loss of the antiangiogenic pigment epithelium-derived factor in patients with angiogenic eye disease.
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