SLC7A5 monoclonal antibody, clone 4D9
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More Files
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Immunohistochemistry
Immunohistochemical analysis of human syncytiotrophoblast tissue, using SLC7A5 monoclonal antibody, clone 4D9 (Cat # MAB1711) .
Immunohistochemistry
Immunohistochemical analysis of human stomach papillary adenocarcinoma tissue, using SLC7A5 monoclonal antibody, clone 4D9 (Cat # MAB1711) .
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of SLC7A5.
Immunogen
A synthetic peptide corresponding to human SLC7A5.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgM
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Immunohistochemistry (2-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.1% BSA, 0.1% proclin)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry
Immunohistochemical analysis of human syncytiotrophoblast tissue, using SLC7A5 monoclonal antibody, clone 4D9 (Cat # MAB1711) .Immunohistochemistry
Immunohistochemical analysis of human stomach papillary adenocarcinoma tissue, using SLC7A5 monoclonal antibody, clone 4D9 (Cat # MAB1711) . -
Gene Info — SLC7A5
Entrez GeneID
8140Gene Name
SLC7A5
Gene Alias
4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1
Gene Description
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
Omim ID
600182Gene Ontology
HyperlinkGene Summary
y+ system)
Other Designations
4F2 light chain|CD98 light chain|L-type amino acid transporter 1|integral membrane protein E16|large neutral amino acids transporter 1|large neutral amino acids transporter small subunit 1|sodium-independent neutral amino acid transporter LAT1
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Interactome
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Disease
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Publication Reference
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Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines.
Yanagida O, Kanai Y, Chairoungdua A, Kim DK, Segawa H, Nii T, Cha SH, Matsuo H, Fukushima J, Fukasawa Y, Tani Y, Taketani Y, Uchino H, Kim JY, Inatomi J, Okayasu I, Miyamoto K, Takeda E, Goya T, Endou H.
Biochimica et Biophysica Acta 2001 Oct; 1514(2):291.
Application：WB-Ce, Human, T24 cells.
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Expression of a system L neutral amino acid transporter at the blood-brain barrier.
Matsuo H, Tsukada S, Nakata T, Chairoungdua A, Kim DK, Cha SH, Inatomi J, Yorifuji H, Fukuda J, Endou H, Kanai Y.
Neuroreport 2000 Nov; 11(16):3507.
Application：IF, IHC, Rat, Brain.
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Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family.
Mastroberardino L, Spindler B, Pfeiffer R, Skelly PJ, Loffing J, Shoemaker CB, Verrey F.
Nature 1998 Sep; 395(6699):288.
Application：IF, IHC, Frog, Frog oocyte sections.
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Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98).
Kanai Y, Segawa H, Miyamoto K, Uchino H, Takeda E, Endou H.
The Journal of Biological Chemistry 1998 Sep; 273(37):23629.
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Family of neutral and acidic amino acid transporters: molecular biology, physiology and medical implications.
Kanai Y.
Current Opinion in Cell Biology 1997 Aug; 9(4):565.
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Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines.
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