DLG4 monoclonal antibody, clone RM288
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot (Tissue lysate) analysis of mouse brain.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human DLG4.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to N-terminus of human DLG4.
Reactivity
Human, Mouse, Rat
Specificity
This antibody reacts to human and mouse DLG4 (Disks large homolog 4). It may also react to rat DLG4, as predicted by immunogen homology.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-200)
Western Blot (1:1000-8000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot (Tissue lysate) analysis of mouse brain.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain. -
Gene Info — DLG4
Entrez GeneID
1742Gene Name
DLG4
Gene Alias
FLJ97752, FLJ98574, PSD95, SAP-90, SAP90
Gene Description
discs, large homolog 4 (Drosophila)
Omim ID
602887Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Tax interaction protein 15|discs large homolog 4|post-synaptic density protein 95|synapse-associated protein 90
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Interactome
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Disease
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