TTR monoclonal antibody, clone 6F11B2
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: HEK293 cell; Lane 2: TTR-hIgGFc transfected HEK293 cell with TTR monoclonal antibody.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of TTR monoclonal antibody, clone 6F11B2.
Flow Cytometry
Flow cytometric analysis of HepG2 cells with TTR monoclonal antibody (green) and negative control (red).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human TTR.
Immunogen
Recombinant protein corresponding to amino acid 1-147 of human TTR from E. coli.
Host
Mouse
Theoretical MW (kDa)
16
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry
Immunocytochemistry
Flow Cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: HEK293 cell; Lane 2: TTR-hIgGFc transfected HEK293 cell with TTR monoclonal antibody.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of TTR monoclonal antibody, clone 6F11B2.Flow Cytometry
Flow cytometric analysis of HepG2 cells with TTR monoclonal antibody (green) and negative control (red). -
Gene Info — TTR
Entrez GeneID
7276Gene Name
TTR
Gene Alias
HsT2651, PALB, TBPA
Gene Description
transthyretin
Omim ID
176300Gene Ontology
HyperlinkGene Summary
This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq
Other Designations
prealbumin, amyloidosis type I|thyroxine-binding prealbumin
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Interactome
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Disease
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