CSF1R monoclonal antibody, clone 4C9G2
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: HEK293 cell; Lane 2: CSF1R-hIgGFc transfected HEK293 cell with CSF1R monoclonal antibody.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of CSF1R monoclonal antibody, clone 4C9G2.
Flow Cytometry
Flow cytometric analysis of Hela cells with CSF1R monoclonal antibody (green) and negative control (red).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human CSF1R.
Immunogen
Recombinant protein corresponding to amino acid 20-152 of human CSF1R from E. coli.
Host
Mouse
Theoretical MW (kDa)
108
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry
Immunocytochemistry
Flow Cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: HEK293 cell; Lane 2: CSF1R-hIgGFc transfected HEK293 cell with CSF1R monoclonal antibody.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of CSF1R monoclonal antibody, clone 4C9G2.Flow Cytometry
Flow cytometric analysis of Hela cells with CSF1R monoclonal antibody (green) and negative control (red). -
Gene Info — CSF1R
Entrez GeneID
1436Gene Name
CSF1R
Gene Alias
C-FMS, CD115, CSFR, FIM2, FMS
Gene Description
colony stimulating factor 1 receptor
Omim ID
164770Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq
Other Designations
CD115 antigen|FMS proto-oncogene|McDonough feline sarcoma viral (v-fms) oncogene homolog|macrophage colony stimulating factor I receptor|soluble CSF1R variant 1
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Interactome
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Pathway
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Disease
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