RANGAP1 monoclonal antibody, clone 4F9E2
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: HEK293 cell; Lane 2: RANGAP1-hIgGFc transfected HEK293 cell with RANGAP1 monoclonal antibody.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of RANGAP1 monoclonal antibody, clone 4F9E2.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human RANGAP1.
Immunogen
Recombinant protein corresponding to amino acid 359-587 of human RANGAP1 from E. coli.
Host
Mouse
Theoretical MW (kDa)
63.5
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: HEK293 cell; Lane 2: RANGAP1-hIgGFc transfected HEK293 cell with RANGAP1 monoclonal antibody.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of RANGAP1 monoclonal antibody, clone 4F9E2. -
Gene Info — RANGAP1
Entrez GeneID
5905Gene Name
RANGAP1
Gene Alias
Fug1, KIAA1835, MGC20266, SD
Gene Description
Ran GTPase activating protein 1
Omim ID
602362Gene Ontology
HyperlinkGene Summary
RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle. [provided by RefSeq
Other Designations
OTTHUMP00000028918|segregation distorter homolog|segregation distortion
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