PIK3CG monoclonal antibody, clone 4B5D2
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human PIK3CG.
Immunogen
Recombinant protein corresponding to amino acid 1-100 of human PIK3CG from E. coli.
Host
Mouse
Theoretical MW (kDa)
126.5
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: HEK293 cell; Lane 2: PIK3CG-hIgGFc transfected HEK293 cell with PIK3CG monoclonal antibody.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of PIK3CG monoclonal antibody, clone 4B5D2. -
Gene Info — PIK3CG
Entrez GeneID
5294Gene Name
PIK3CG
Gene Alias
PI3CG, PI3K, PI3Kgamma, PIK3
Gene Description
phosphoinositide-3-kinase, catalytic, gamma polypeptide
Omim ID
601232Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq
Other Designations
1-phosphatidylinositol 3-kinase|PI3-kinase|PTDINS-3-kinase|p110-gamma|phosphatidylinositol 3 kinase gamma, p110 gamma|phosphatidylinositol 3-kinase catalytic 110-kD gamma|phosphatidylinositol 3-kinase, catalytic, gamma polypeptide|phosphoinositide-3-kinas
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Interactome
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Disease
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