ENG monoclonal antibody, clone 8A1
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of HEK293T cells (Lane 1: transfected with pCMV6-ENTRY control and Lane 2: transfected with pCMV6-ENTRY ENG cDNA) with ENG monoclonal antibody, clone 8A1 (Cat # MAB16370).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with ENG monoclonal antibody, clone 8A1 (Cat # MAB16370).
Immunofluorescence
Immunofluorescent staining of HeLa cells with ENG monoclonal antibody, clone 8A1 (Cat # MAB16370).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human ENG.
Immunogen
Recombinant protein corresponding to full length human ENG from HEK293T cell.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2b
Recommend Usage
Immunofluorescence (1:100)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
Western Blot (1:200-1:4000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.3 (50% glycerol, 1% BSA, 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HEK293T cells (Lane 1: transfected with pCMV6-ENTRY control and Lane 2: transfected with pCMV6-ENTRY ENG cDNA) with ENG monoclonal antibody, clone 8A1 (Cat # MAB16370).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human spleen with ENG monoclonal antibody, clone 8A1 (Cat # MAB16370).Immunofluorescence
Immunofluorescent staining of HeLa cells with ENG monoclonal antibody, clone 8A1 (Cat # MAB16370). -
Gene Info — ENG
Entrez GeneID
2022Protein Accession#
P17813Gene Name
ENG
Gene Alias
CD105, END, FLJ41744, HHT1, ORW, ORW1
Gene Description
endoglin
Gene Ontology
HyperlinkGene Summary
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CD105 antigen|OTTHUMP00000022221|Osler-Rendu-Weber syndrome 1
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Interactome
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Disease
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