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Last updated: 2019/10/13

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FMR1 monoclonal antibody, clone 1D10 

  • Catalog # : MAB16366
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human FMR1.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 36-279 of human FMR1 from E. coli.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 1% BSA, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of HEK293T cells (Lane 1: transfected with pCMV6-ENTRY control and Lane 2: transfected with pCMV6-ENTRY FMR1 cDNA) with FMR1 monoclonal antibody, clone 1D10 (Cat # MAB16366).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung with FMR1 monoclonal antibody, clone 1D10 (Cat # MAB16366).
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2332
  • Gene Name:
  • FMR1
  • Gene Alias:
  • FMRP,FRAXA,MGC87458,POF,POF1
  • Gene Description:
  • fragile X mental retardation 1
  • Gene Summary:
  • The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000024197,premature ovarian failure 1
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