ADK monoclonal antibody, clone AT4F8
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: HepG2 and Lane 2: 293T cell lysates with ADK monoclonal antibody, clone AT4F8 (Cat # MAB16188).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with ADK monoclonal antibody, clone AT4F8 (Cat # MAB16188).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human ADK.
Immunogen
Recombinant protein corresponding to human ADK.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
ELISA
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: HepG2 and Lane 2: 293T cell lysates with ADK monoclonal antibody, clone AT4F8 (Cat # MAB16188).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with ADK monoclonal antibody, clone AT4F8 (Cat # MAB16188).Enzyme-linked Immunoabsorbent Assay
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Gene Info — ADK
Entrez GeneID
132Protein Accession#
P55263Gene Name
ADK
Gene Alias
AK
Gene Description
adenosine kinase
Omim ID
102750Gene Ontology
HyperlinkGene Summary
This gene encodes adenosine kinase, an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity. [provided by RefSeq
Other Designations
OTTHUMP00000019864|OTTHUMP00000019865|adenosine 5'-phosphotransferase
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Interactome
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Pathway
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Disease
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