AKR1C1 monoclonal antibody, clone AT6D10
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of HepG2 cell lysate (Lane 1: 1:500, Lane 2: 1:1000 and Lane 3: 1:5000) with AKR1C1 monoclonal antibody, clone AT6D10 (Cat # MAB16185).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with AKR1C1 monoclonal antibody, clone AT6D10 (Cat # MAB16185).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human AKR1C1.
Immunogen
Recombinant protein corresponding to human AKR1C1.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG1, kappa
Recommend Usage
ELISA
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HepG2 cell lysate (Lane 1: 1:500, Lane 2: 1:1000 and Lane 3: 1:5000) with AKR1C1 monoclonal antibody, clone AT6D10 (Cat # MAB16185).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with AKR1C1 monoclonal antibody, clone AT6D10 (Cat # MAB16185).Enzyme-linked Immunoabsorbent Assay
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Gene Info — AKR1C1
Entrez GeneID
1645Protein Accession#
Q04828Gene Name
AKR1C1
Gene Alias
2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DDH, DDH1, H-37, HAKRC, MBAB, MGC8954
Gene Description
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
Omim ID
600449Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq
Other Designations
20 alpha-hydroxysteroid dehydrogenase|OTTHUMP00000018992|aldo-keto reductase C|aldo-keto reductase family 1, member C1|chlordecone reductase homolog|dihydrodiol dehydrogenase 1|dihydrodiol dehydrogenase isoform DD1|hepatic dihydrodiol dehydrogenase|trans-
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Interactome
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Disease
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