BMF monoclonal antibody, clone 9G10
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Specification
Product Description
Rat monoclonal antibody raised against recombinant human BMF.
Immunogen
Recombinant protein corresponding to mouse BMF.
Host
Rat
Reactivity
Human, Mouse
Form
Liquid
Purification
>95% (SDS-PAGE)
Isotype
IgG2a, kappa
Recommend Usage
Flow Cytometry (overexpressed in cell lines)
Immunoprecipitation (1-5 ug/mL)
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide).
Storage Instruction
For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunoprecipitation
Flow Cytometry
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Gene Info — BMF
Entrez GeneID
90427Protein Accession#
Q96LC9Gene Name
BMF
Gene Alias
FLJ00065
Gene Description
Bcl2 modifying factor
Omim ID
606266Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
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Interactome
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Disease
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