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Last updated: 2017/12/10

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IFIH1 monoclonal antibody, clone Hely-1

  • Catalog # : MAB16090
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombiant human IFIH1.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 78-555 of human IFIH1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • >95% (SDS-PAGE)
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunoprecipitation (1:100)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (10% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunoprecipitation
  • Gene Information
  • Gene Name:
  • IFIH1
  • Gene Alias:
  • Hlcd,IDDM19,MDA-5,MDA5,MGC133047
  • Gene Description:
  • interferon induced with helicase C domain 1
  • Gene Summary:
  • DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. [provided by RefSeq
  • Other Designations:
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide,helicard,melanoma differentiation associated protein-5
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