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SIRT2 monoclonal antibody, clone S2R233-1

  • Catalog # : MAB16061
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombiant human SIRT2.
  • Immunogen:
  • Recombinant protein corresponding to human SIRT2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • ELISA (1:2000-5000)
    Western Blot (1:2000-5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4.
  • Storage Instruction:
  • For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • ELISA
  • Application Image
  • Western Blot
  • ELISA
  • Gene Information
  • Gene Name:
  • SIRT2
  • Gene Alias:
  • SIR2,SIR2L,SIR2L2
  • Gene Description:
  • sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene. [provided by RefSeq
  • Other Designations:
  • silencing information regulator 2-like,silent information regulator 2,sir2-related protein type 2,sirtuin 2,sirtuin type 2
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