JAG1 monoclonal antibody, clone J1G53-3
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human JAG1.
Immunogen
Recombinant protein corresponding to human JAG1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1, kappa
Recommend Usage
ELISA (1:500-5000)
Flow Cytometry (1:20-100)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Western Blot (1:500-5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4.
Storage Instruction
For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
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Gene Info — JAG1
Entrez GeneID
182Protein Accession#
P78504Gene Name
JAG1
Gene Alias
AGS, AHD, AWS, CD339, HJ1, JAGL1, MGC104644
Gene Description
jagged 1 (Alagille syndrome)
Gene Ontology
HyperlinkGene Summary
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq
Other Designations
OTTHUMP00000030278|jagged 1
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Interactome
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Pathway
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Disease
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