NAMPT monoclonal antibody, clone OMNI379
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human NAMPT.
Immunogen
Recombinant protein corresponding to human NAMPT.
Host
Mouse
Reactivity
Human, Mouse, Rat
Form
Liquid
Isotype
IgG2a, kappa
Recommend Usage
ELISA (1:2000-10000)
Flow Cytometry (1:1000)
Immunocytochemistry (1:500-1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-500)
Immunoprecipitation (1:500-1000)
Western Blot (1:2000-5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4.
Storage Instruction
For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
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Gene Info — NAMPT
Entrez GeneID
10135Protein Accession#
P43490Gene Name
NAMPT
Gene Alias
1110035O14Rik, DKFZp666B131, MGC117256, PBEF, PBEF1, VF, VISFATIN
Gene Description
nicotinamide phosphoribosyltransferase
Omim ID
608764Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. This gene has a pseudogene on chromosome 10. [provided by RefSeq
Other Designations
NAmPRTase|pre-B cell-enhancing factor|pre-B-cell colony enhancing factor 1
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Interactome
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Pathway
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Disease
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