MME monoclonal antibody, clone K16-P (FITC)
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes with MME monoclonal antibody, clone K16-P (FITC) (Cat # MAB16005).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human MME.
Host
Rabbit
Reactivity
Human
Form
Liquid
Conjugation
FITC
Purification
EVAC purification
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (10 mg/mL BSA, 0.05% Sodium Azide).
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes with MME monoclonal antibody, clone K16-P (FITC) (Cat # MAB16005). -
Gene Info — MME
Entrez GeneID
4311Protein Accession#
P08473Gene Name
MME
Gene Alias
CALLA, CD10, DKFZp686O16152, MGC126681, MGC126707, NEP
Gene Description
membrane metallo-endopeptidase
Omim ID
120520Gene Ontology
HyperlinkGene Summary
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq
Other Designations
atriopeptidase|common acute lymphocytic leukemia antigen|enkephalinase|membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)|membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)|membrane metallo-endopeptidase
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Interactome
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Pathway
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Disease
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