PRKCG monoclonal antibody, clone K21-L (FITC)
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More Files
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Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes with PRKCG monoclonal antibody, clone K21-L (FITC) (Cat # MAB15993).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human PRKCG.
Host
Rabbit
Reactivity
Human
Form
Liquid
Conjugation
FITC
Purification
EVAC purification
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (10 mg/mL BSA, 0.05% Sodium Azide).
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes with PRKCG monoclonal antibody, clone K21-L (FITC) (Cat # MAB15993). -
Gene Info — PRKCG
Entrez GeneID
5582Protein Accession#
P05129Gene Name
PRKCG
Gene Alias
MGC57564, PKC-gamma, PKCC, PKCG, SCA14
Gene Description
protein kinase C, gamma
Gene Ontology
HyperlinkGene Summary
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq
Other Designations
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