C3 monoclonal antibody, clone E28-P
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human C3.
Immunogen
A synthetic peptide corresponding to N-terminus of human C3d complement fragment.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
EVAC purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM Tris-HCl buffer, pH 8.0 (20 mg/mL BSA, 0.05% Sodium Azide).
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin biopsy from the lesion of the early pemphigus vulgaris with C3 monoclonal antibody, clone E28-P (Cat # MAB15963). -
Gene Info — C3
Entrez GeneID
718Protein Accession#
P01024Gene Name
C3
Gene Alias
ARMD9, ASP, CPAMD1
Gene Description
complement component 3
Omim ID
120700Gene Ontology
HyperlinkGene Summary
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection. [provided by RefSeq
Other Designations
acylation-stimulating protein cleavage product|complement component C3
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Interactome
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Pathway
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Disease
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Publication Reference
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Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury.
De Hoog VC, Timmers L, Van Duijvenvoorde A, De Jager SC, Van Middelaar BJ, Smeets MB, Woodruff TM, Doevendans PA, Pasterkamp G, Hack CE, De Kleijn DP.
Cardiovascular Research 2014 Sep; 103(4):521.
Application:IHC-P, Mouse, Ventricles.
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Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury.
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