S100A1 monoclonal antibody, clone D28-E
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human S100A1.
Immunogen
A synthetic peptide corresponding to C-terminus of human S100A1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
EVAC purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM Tris-HCl buffer, pH 8.0 (20 mg/mL BSA, 0.05% Sodium Azide).
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cutaneous malignant melanoma with S100A1 monoclonal antibody, clone D28-E (Cat # MAB15943). -
Gene Info — S100A1
Entrez GeneID
6271Protein Accession#
P23297Gene Name
S100A1
Gene Alias
S100, S100-alpha, S100A
Gene Description
S100 calcium binding protein A1
Omim ID
176940Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq
Other Designations
OTTHUMP00000035100|S100 alpha|S100 calcium-binding protein A1|S100 protein, alpha polypeptide
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Interactome
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Disease
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Publication Reference
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Immunohistochemical markers for the differential diagnosis of nephrogenic adenomas.
Quinones W, Ziober A, Yao Y, Bing Z.
Annals of Diagnostic Pathology 2013 Feb; 17(1):41.
Application:IHC-P, Human, Human nephrogenic adenoma.
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Immunohistochemical markers for the differential diagnosis of nephrogenic adenomas.
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