KRT7 monoclonal antibody, clone R17-S
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human KRT7.
Immunogen
A synthetic peptide corresponding to N-terminus of human KRT7.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
EVAC purification
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM Tris-HCl buffer, pH 8.0 (20 mg/mL BSA, 0.05% Sodium Azide).
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human ductal pancreatic adenocarcinoma with KRT7 monoclonal antibody, clone R17-S (Cat # MAB15941). -
Gene Info — KRT7
Entrez GeneID
3855Protein Accession#
P08729Gene Name
KRT7
Gene Alias
CK7, K2C7, K7, MGC129731, MGC3625, SCL
Gene Description
keratin 7
Omim ID
148059Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq
Other Designations
cytokeratin 7|keratin, 55K type II cytoskeletal|keratin, simple epithelial type I, K7|keratin, type II cytoskeletal 7|sarcolectin|type II mesothelial keratin K7
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Interactome
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Publication Reference
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An immunohistochemical study on the expression of sex steroid receptors, Ki-67 and cytokeratins 7 and 20 in feline endometrial adenocarcinomas.
Saraiva AL, Payan-Carreira R, Gärtner F, Fortuna da Cunha MR, Rêma A, Faria F, Lourenço LM, Pires Mdos A.
BMC Veterinary Research 2015 Aug; 11:204.
Application:IHC-P, Human, Endometrial adenocarcinomas.
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Foamy cell angiosarcoma is a diagnostic pitfall: a case report of an angiosarcoma mimicking xanthoma.
Svajdler M, Benicky M, Frohlichova L, Benes T, Hojstricova Z, Kazakov DV.
The American Journal of Dermatopathology 2014 Aug; 36(8):669.
Application:IHC, Human, Human angiosarcoma.
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Fibroblast α11β1 integrin regulates tensional homeostasis in fibroblast/A549 carcinoma heterospheroids.
Lu N, Karlsen TV, Reed RK, Kusche-Gullberg M, Gullberg D.
PLoS One 2014 Jul; 9(7):e103173.
Application:IF, Human, A-549 cells.
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An immunohistochemical study on the expression of sex steroid receptors, Ki-67 and cytokeratins 7 and 20 in feline endometrial adenocarcinomas.
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