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MAPK14 monoclonal antibody, clone E17-S

  • Catalog # : MAB15918
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human MAPK14.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 345-359 at C-terminus of human MAPK14.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • EVAC purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • ELISA (1:20000-1:40000)
    Immunocytochemistry
    Immunoprecipitation
    Western Blot (1:5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM Tris-HCl buffer, pH 8.0 (10 mg/mL BSA, 0.05% Sodium Azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western Blot analysis of Lane 1: MAPK14 recombinant protein 500 ng, Lane 2: MAPK11 recombinant protein 500 ng, Lane 3: MAPK12 recombinant protein 500 ng and Lane 4: MAPK13 recombinant protein 500 ng with MAPK14 monoclonal antibody, clone E17-S (Cat # MAB15918).
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemical staining of HEK293 cells with MAPK14 monoclonal antibody, clone E17-S (Cat # MAB15918) at 1:300 dilution.
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1432
  • Gene Name:
  • MAPK14
  • Gene Alias:
  • CSBP1,CSBP2,CSPB1,EXIP,Mxi2,PRKM14,PRKM15,RK,SAPK2A,p38,p38ALPHA
  • Gene Description:
  • mitogen-activated protein kinase 14
  • Gene Summary:
  • The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • Csaids binding protein,MAP kinase Mxi2,MAX-interacting protein 2,cytokine suppressive anti-inflammatory drug binding protein,p38 MAP kinase,p38 mitogen activated protein kinase,p38alpha Exip,stress-activated protein kinase 2A
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