Product Browser

Last updated: 2017/12/10

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

PRNP monoclonal antibody, clone V21-V

  • Catalog # : MAB15909
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human PRNP.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 161-177 at internal region of the second alpha-helical domain of human PRNP.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • EVAC purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • ELISA (1:20000-1:50000)
    Immunoprecipitation
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM Tris-HCl buffer, pH 8.0 (10 mg/mL BSA, 0.05% Sodium Azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of Lane 1: mouse brain tissue lysate, HEK293 cells Lane 2: transfected with PRNP recombinant protein and Lane 3: untransfected with PRNP monoclonal antibody, clone V21-V (Cat # MAB15909).
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5621
  • Gene Name:
  • PRNP
  • Gene Alias:
  • ASCR,CD230,CJD,GSS,MGC26679,PRIP,PrP,PrP27-30,PrP33-35C,PrPc,prion
  • Gene Description:
  • prion protein
  • Gene Summary:
  • The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
  • Other Designations:
  • CD230 antigen,OTTHUMP00000030162,OTTHUMP00000030163,major prion protein,p27-30,prion protein PrP,prion-related protein
  • Gene Pathway
  • RSS
  • YouTube
  • Linkedin
  • Facebook