TNFRSF18 monoclonal antibody, clone AIT 158D
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Specification
Product Description
Rat monoclonal antibody raised against human TNFRSF18.
Immunogen
Recombinant protein corresponding to human TNFRSF18.
Host
Rat
Reactivity
Human
Form
Liquid
Isotype
IgG2a, kappa
Recommend Usage
ELISA (1:5000-1:10000)
Flow Cytometry (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4.
Storage Instruction
For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
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Gene Info — TNFRSF18
Entrez GeneID
8784Protein Accession#
Q9Y5U5Gene Name
TNFRSF18
Gene Alias
AITR, GITR, GITR-D
Gene Description
tumor necrosis factor receptor superfamily, member 18
Omim ID
603905Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000001519|OTTHUMP00000001520|OTTHUMP00000001521|TNF receptor superfamily activation-inducible protein|activation-inducible TNFR family receptor|glucocorticoid-induced TNFR-related protein
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Interactome
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