PFN1 monoclonal antibody, clone CL3524
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human PFN1.
Immunogen
Recombinant protein corresponding to human PFN1.
Sequence
KSIGGAPTFNVTVTKTDKTLVLLMGKEGIHG
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG2a
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:2500)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: HeLa, Lane 2: HEK 293, Lane 3: A-431 and Lane 4: HepG2 cell lysates with PFN1 monoclonal antibody, clone CL3524 (Cat # MAB15805).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human fallopian tube with PFN1 monoclonal antibody, clone CL3524 (Cat # MAB15805) shows cytoplasmic immunoreactivity in epithelial cells. -
Gene Info — PFN1
Entrez GeneID
5216Protein Accession#
P07737Gene Name
PFN1
Gene Alias
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Gene Description
profilin 1
Omim ID
176610Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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