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SSX2 monoclonal antibody, clone CL3202

  • Catalog # : MAB15795
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human SSX2.
  • Immunogen:
  • Recombinant protein corresponding to human SSX2.
  • Sequence:
  • GKHAWTHRLRERKQLVIYEEISDPEEDDE
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:2500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Epitope:
  • This antibody binds to an epitope located within the peptide sequence GKHAWTHRLRERKQL as determined by overlapping synthetic peptides.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with SSX2 monoclonal antibody, clone CL3202 (Cat # MAB15795) shows strong nuclear immunoreactivity in a subset of cells in seminiferous tubules.
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6757
  • Gene Name:
  • SSX2
  • Gene Alias:
  • HD21,HOM-MEL-40,MGC119055,MGC15364,MGC3884,SSX
  • Gene Description:
  • synovial sarcoma, X breakpoint 2
  • Gene Summary:
  • The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000024290,OTTHUMP00000024291,sarcoma, synovial, X-chromosome-related 2,synovial sarcoma, X breakpoint 2, isoform b,synovial sarcoma, X breakpoint 2B
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