LAMA5 monoclonal antibody, clone CL3118
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human LAMA5.
Immunogen
Recombinant protein corresponding to human LAMA5.
Epitope
This antibody binds to an epitope located within the peptide sequence RQGLVDRAQQ as determined by overlapping synthetic peptides.
Sequence
LNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQQRLGLVWAAL
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human placenta tissue lysate with LAMA5 monoclonal antibody, clone CL3118 (Cat # MAB15790).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with LAMA5 monoclonal antibody, clone CL3118 (Cat # MAB15790) shows strong immunoreactivity in basement membrane of renal tubules and membranous positivity in glomeruli. -
Gene Info — LAMA5
Entrez GeneID
3911Protein Accession#
O15230Gene Name
LAMA5
Gene Alias
KIAA1907
Gene Description
laminin, alpha 5
Omim ID
601033Gene Ontology
HyperlinkGene Summary
Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined. [provided by RefSeq
Other Designations
laminin alpha 5|laminin alpha-5 chain
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Interactome
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