MOG monoclonal antibody, clone CL2852
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human MOG.
Immunogen
Recombinant protein corresponding to human MOG.
Epitope
This antibody binds to an epitope located within the peptide sequence FSRVVHLYRNGKDQD as determined by overlapping synthetic peptides.
Sequence
ALVGDEVELPCRISPGKNATGMEVGWYRPPFSRVVHLYRNGKDQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDPFYWVSPG
Host
Mouse
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:2500)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human cerebral cortex tissue lysate with MOG monoclonal antibody, clone CL2852 (Cat # MAB15776).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebral cortex with MOG monoclonal antibody, clone CL2852 (Cat # MAB15776) shows strong immunoreactivity in myelinated neural fibers. -
Gene Info — MOG
Entrez GeneID
4340Protein Accession#
Q16653Gene Name
MOG
Gene Alias
MGC26137, MOGIG-2
Gene Description
myelin oligodendrocyte glycoprotein
Omim ID
159465Gene Ontology
HyperlinkGene Summary
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
MOG Ig-AluB|MOG alpha-6|OTTHUMP00000029122|OTTHUMP00000029124|OTTHUMP00000029125|OTTHUMP00000029126|OTTHUMP00000029127
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Interactome
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Disease
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