HNRNPC monoclonal antibody, clone CL2593
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of U-251 MG cell lysate with HNRNPC monoclonal antibody, clone CL2593 (Cat # MAB15759).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with HNRNPC monoclonal antibody, clone CL2593 (Cat # MAB15759) shows strong nuclear immunoreactivity in glandular and lamina propria cells.
Immunofluorescence
Immunofluorescent staining of MCF7 cells with HNRNPC monoclonal antibody, clone CL2593 (Cat # MAB15759) (Green) shows distinct nuclear (without nucleoli). Microtubule and nuclear probes are visualized in red and blue respectively (where available).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human HNRNPC.
Immunogen
Recombinant protein corresponding to human HNRNPC.
Sequence
AEMYGSVTEHPSPSPLLSSS
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG2a
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:2500)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of U-251 MG cell lysate with HNRNPC monoclonal antibody, clone CL2593 (Cat # MAB15759).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human rectum with HNRNPC monoclonal antibody, clone CL2593 (Cat # MAB15759) shows strong nuclear immunoreactivity in glandular and lamina propria cells.Immunofluorescence
Immunofluorescent staining of MCF7 cells with HNRNPC monoclonal antibody, clone CL2593 (Cat # MAB15759) (Green) shows distinct nuclear (without nucleoli). Microtubule and nuclear probes are visualized in red and blue respectively (where available). -
Gene Info — HNRNPC
Entrez GeneID
3183Protein Accession#
P07910Gene Name
HNRNPC
Gene Alias
C1, C2, HNRNP, HNRPC, MGC104306, MGC105117, MGC117353, MGC131677, SNRPC
Gene Description
heterogeneous nuclear ribonucleoprotein C (C1/C2)
Omim ID
164020Gene Ontology
HyperlinkGene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq
Other Designations
heterogeneous nuclear ribonucleoprotein C|nuclear ribonucleoprotein particle C1 protein|nuclear ribonucleoprotein particle C2 protein
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