VWF monoclonal antibody, clone CL1950
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot analysis of human plasma tissue lysate with VWF monoclonal antibody, clone CL1950 (Cat # MAB15724).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with VWF monoclonal antibody, clone CL1950 (Cat # MAB15724) shows strong immunoreactivity in blood vessels and in plasma.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human VWF.
Immunogen
Recombinant protein corresponding to human VWF.
Epitope
This antibody binds to an epitope located within the peptide sequence RYDAAQLRIL as determined by overlapping synthetic peptides.
Sequence
ARSNRVTVFPIGIGDRYDAAQLRILAGPAGDSNVVKLQRIEDLPTMVTLGNSFLHKLCSGFVRICMDEDGNEKRPGDVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEKT
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG2a
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:2500)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human plasma tissue lysate with VWF monoclonal antibody, clone CL1950 (Cat # MAB15724).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with VWF monoclonal antibody, clone CL1950 (Cat # MAB15724) shows strong immunoreactivity in blood vessels and in plasma. -
Gene Info — VWF
Entrez GeneID
7450Protein Accession#
P04275Gene Name
VWF
Gene Alias
F8VWF, VWD
Gene Description
von Willebrand factor
Omim ID
193400Gene Ontology
HyperlinkGene Summary
The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq
Other Designations
coagulation factor VIII VWF
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Interactome
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Pathway
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Disease
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