ITGAX monoclonal antibody, clone CL1831
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot analysis of human tonsil tissue lysate with ITGAX monoclonal antibody, clone CL1831 (Cat # MAB15721).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with ITGAX monoclonal antibody, clone CL1831 (Cat # MAB15721) shows strong immunoreactivity in the dendritic cells.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human ITGAX.
Immunogen
Recombinant protein corresponding to human ITGAX.
Epitope
This antibody binds to an epitope located within the peptide sequence LYIDKRSKNLLGSRD as determined by overlapping synthetic peptides.
Sequence
QDGLVDLAVGARGQVLLLRTRPVLWVGVSMQFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSKNLLGSRDLQSSVTLDLALDPGRLSPRATFQETKNRSLSRVRV
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human tonsil tissue lysate with ITGAX monoclonal antibody, clone CL1831 (Cat # MAB15721).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with ITGAX monoclonal antibody, clone CL1831 (Cat # MAB15721) shows strong immunoreactivity in the dendritic cells. -
Gene Info — ITGAX
Entrez GeneID
3687Protein Accession#
P20702Gene Name
ITGAX
Gene Alias
CD11C, SLEB6
Gene Description
integrin, alpha X (complement component 3 receptor 4 subunit)
Omim ID
151510Gene Ontology
HyperlinkGene Summary
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq
Other Designations
OTTHUMP00000163299|integrin alpha X|integrin, alpha X (antigen CD11C (p150), alpha polypeptide)|leu M5, alpha subunit|leukocyte surface antigen p150,95, alpha subunit|myeloid membrane antigen, alpha subunit|p150 95 integrin alpha chain
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Interactome
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Pathway
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Disease
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