MKL1 monoclonal antibody, clone CL4281
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of HL-60 cell lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lymph node shows moderate immunoreactivity in a subset of lymphoid cells.
-
Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human MKL1.
Immunogen
Recombinant protein corresponding to human MKL1.
Epitope
This antibody binds to an epitope located within the peptide sequence PTLITDSTGTHLVLT as determined by overlapping synthetic peptides.
Sequence
EQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPG
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of HL-60 cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lymph node shows moderate immunoreactivity in a subset of lymphoid cells. -
Gene Info — MKL1
Entrez GeneID
57591Protein Accession#
Q969V6Gene Name
MKL1
Gene Alias
BSAC, MAL, MRTF-A
Gene Description
megakaryoblastic leukemia (translocation) 1
Omim ID
606078Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. [provided by RefSeq
Other Designations
OTTHUMP00000028831|RBM15/MKL1 fusion|RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein|basic, SAP and coiled-coil domain|megakaryoblastic leukemia 1|megakaryoblastic leukemia 1 protein|megakaryocytic acute leukemia|myocardin-related
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com